Robotics Engineer for Automation of Ultrathin Brain Sectioning
The FlyWire Consortium, led by the Princeton Neuroscience Institute, recently released the first neuronal wiring diagram of an adult brain. The fruit fly connectome was obtained by processing electron microscopic brain images to reconstruct tens of millions of synapses between 100,000 neurons. With this historic milestone attained, neuroscience has clearly entered the connectomic era.
The image processing benefited from modern high performance computing and artificial intelligence. But the images were acquired from slices of the fly brain that were collected manually, in a manner that has remained essentially unchanged for over 50 years. We are building an engineering team to modernize the collection of ultrathin brain slices with a pick-and-place robot guided by computer vision. The task is to pick up slices floating on water and place them on substrates suitable for electron microscopic imaging. This is the kind of technological innovation necessary to scale up connectomics from flies to large mammalian brains more like our own.
We are seeking a robotics engineer to design and build the robot, interface it with a control system, and collaborate with a robot vision engineer to control the pick and place operations.
This full-time position has an initial appointment of one year and possibility of renewal based on satisfactory performance. For more information, see these publications.
Timothy J. Lee et al. Large-scale neuroanatomy using LASSO: loop-based automated serial sectioning operation. PLoS One 13:e0206172 (2018).
John Ngai. BRAIN 2.0: Transforming neuroscience. Cell 185, 4-8 (2022).
Sven Dorkenwald et al. Neuronal wiring diagram of an adult brain. bioRxiv 2023.
Responsibilities
Key Responsibilities :
Essential Qualifications:
Preferred Qualifications:
Princeton University is an Equal Opportunity/Affirmative Action Employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability status, protected veteran status, or any other characteristic protected by law. KNOW YOUR RIGHTS
Standard Weekly Hours36.25Eligible for OvertimeNoBenefits EligibleYesEssential Services Personnel (see policy for detail)NoEstimated Appointment End Date5/1/2025Comments Related to End DateThis full-time position has an initial appointment of one year and possibility of renewal based on satisfactory performance. Physical Capacity Exam RequiredNoValid Driver’s License RequiredNo Experience LevelAssociate...interested in working with small teams of highly talented and motivated engineers seeking to make a difference in the world, Gen Nine may be the... .... Position We're seeking results-orientated, neuromorphic AI engineers interested in exploring new concepts in health and...
...Position: EHS Manager Primary Location: Toledo/Oregon, OH (ON-SITE) Reports to: Regional EHS Manager Compensation: $117,000-$125,000 (USD) Salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum...
The Audio & Media Technologies (AMT) group is at the center of Apples innovative products, including the Mac, iPhone, iPad, Apple Watch... ...to enrich our platforms. The team is seeking a triage engineer embedded in the Audio Hardware Abstraction Layer (HAL) team. As...
...Overview NYC 299 Park Avenue (22957), United States of America, New York, New York AI Engineer At Capital One, we are creating responsible and reliable AI systems, changing banking for good. For years, Capital One has been an industry leader in using machine...
...through Friday. The ideal candidate will have excellent communication skill and have a caring and nurturing personality. Live-in accommodations include a private bedroom and bathroom. Nanny should be local to Westport and have flexibility to enjoy weekends off in their...